January, 2007 to present, Assistant Professor, NIPER
2006 – 2007, Lecturer, Birla Institute of Technology and Science, Pilani – Goa campus
2005 – 2006, Postdoctoral research fellow, University of California, Rivesride, USA
2004 – 2005, Postdoctoral research fellow, University of Illinois at Chicago, USA
2002 – 2004, Postdoctoral research fellow, University of Tennessee, Knoxville, USA
2000 – 2002, Lecturer, Raidighi college, University of Calcutta, Kolkata
1996 – 2001, Ph. D., Indian Association for the Cultivation of Science, Kolkata
Research Interests
Design and synthesis of heterocyclic compounds as DNA antimetabolites, and inhibitors of Kinases (especially Aurora A) and Topoisomerase II for structure based discovery of anticancer agents Design and synthesis of heterocyclic compounds as antimalarial agents Synthesis of heterocyclic compounds, Multicomponent reactions (MCR), Tin free radical reactions, Synthetic use of organoboron compounds, Green Chemistry
Publications Dr. Sankar K. Guchhait Assistant Professor Department of Medicinal Chemistry National Institute of Pharmaceutical Education and Research (NIPER) Phase X, Sector 67, S. A. S. Nagar (Mohali), Punjab-160062, India. 17. An Efficient Regioselective Versatile Synthesis of N‐Fused 2‐ and 3‐Aminoimidazoles via Ugitype Multicomponent Reaction Mediated by Zirconium(IV) Chloride in Polyethylene Glycol‐ 400, Sankar K. Guchhait and Chetna Madaan Synlett 2009, 628. 1Click Chemistry: A Novel Approach in Drug Discovery, Chetna Madaan and Sankar K. Guchhait CRIPS, 2008, 9, 11 15. Synthesis and structure‐activity relationships of metal‐ligand complexes that potently inhibit cell migration, Anwar B. Beshir, Sankar K. Guchhait, José A. Gascón and Gabriel Fenteany Bioorg. Med. Chem. Lett. 2008, 18, 498. 14. Green Chemistry: Its Potential Use in Sustainable Synthesis of Pharmaceuticals, Chetna Madaan and Sankar K. Guchhait CRIPS, 2007, 8, 68 13. Convenient Synthesis of α,β‐Unsaturated Phosphonates via a Mizoroki‐Heck Reaction of Arylboronic Acids with Diethyl vinylphosphonate, George W. Kabalka, Sankar K. Guchhait and Abhijit Naravane Tetrahedron Lett . 2004, 45, 4685. 12. Convenient Synthesis of α,β‐Unsaturated Sulfones via a Mizoroki‐Heck Reaction of Arylboronic Acids with Phenyl Vinyl Sulfones, George W. Kabalka and Sankar K. Guchhait, Tetrahedron Lett . 2004, 45, 4021. 11. Synthesis of Diprotected Monosubstituted Hydrazine Derivatives from tert‐Butyl Carbazates and Boronic Acids, George W. Kabalka and Sankar K. Guchhait, Org. Lett. 2003, 5, 4129. 10. Synthesis of (E)‐ and (Z)‐Alkenylphosphonates Using Vinylboronates, George W. Kabalka and Sankar K. Guchhait, Org. Lett. 2003, 5, 729. 9. Zinc Tetrafluoroborate Catalyzed Mannich‐Type Reaction of Aldimines and Silyl Enol Ethers in Aqueous Medium, Brindaban C. Ranu, Sampak Samanta and Sankar K. Guchhait, Tetrahedron 2002, 58, 983. 8. Selective Reduction of Terminal Alkynes to Alkenes by Indium Metal, Brindaban C. Ranu, Jyotirmoy Dutta and Sankar K. Guchhait, J. Org. Chem. 2001, 66, 5624. 7. Indium Metal as a Reducing Agent. Selective Reduction of Carbon‐Carbon Double Bond in Highly Activated Conjugated Alkenes, Brindaban C. Ranu, Jyotirmoy Dutta and Sankar K. Guchhait, Org. Lett. 2001, 3, 2603. 6. Stereoselective Reduction of Aryl‐Substituted gem‐Dibromides to Vinyl Bromides by Indium Metal, Brindaban C. Ranu, Sampak Samanta and Sankar K. Guchhait, J. Org. Chem. 2001, 66, 4102. 5. Construction of Bicyclo[2.2.2]octanone Systems by Microwave‐Assisted Solid Phase Michael Addition Followed by Al2O3‐Mediated Intramolecular Aldolisation. An Eco‐friendly Approach, Brindaban C. Ranu, Sankar K. Guchhait, Keya Ghosh and Amarendra Patra, Green Chemistry, 2000, 5. 4. A Convenient and Efficient Procedure for Selective Deprotection of Acetates by Titanium(IV) Isopropoxides, Brindaban C. Ranu, Sankar K. Guchhait and Manika Saha, J. Indian Chem. Soc. 1999, 76, 547 (special issue dedicated to Professor D. Nasipuri, India on the occasion of his 75th birth anniversary) 3. Stereoselective Debromination of Aryl‐Substituted vic‐Dibromide with Indium Metal, Brindaban C. Ranu, Sankar K. Guchhait and Arunkanti Sarkar, J. Chem. Soc., Chem. Commun., 1998, 2113. 2. Chemoselective Hydrogenation of α, β‐Unsaturated Sulfones and Phosphonates via Palladium‐Assisted Hydrogen Transfer by Ammonium Formate, Brindaban C. Ranu, Sankar K. Guchhait and Keya Ghosh, J. Org. Chem. 1998, 63, 5250. 1. Catalytic Hydrogen Transfer Reductions Using Ammonium Formate. A Review, Brindaban C. Ranu, Arunkanti Sarkar, Sankar K. Guchhait and Keya Ghosh, J. Indian Chem. Soc. 1998, 75, 690‐694 (special issue dedicated to Professor Sukh Dev, India on the occasion of his 75th
birthday).
Getting Started
Click on the edit button above to put your own content on this page.
To invite new members, click on Manage Wiki and Invite People.
To change your wiki's colors or theme, click on Manage Wiki and Look and Feel.
To set who can view and edit your wiki, click on Manage Wiki and Permissions.
Need Help?
Click on the help link above to learn more about how to use your wiki.
Research Interests
Design and synthesis of heterocyclic compounds as DNA antimetabolites, and inhibitors of Kinases (especially Aurora A) and Topoisomerase II for structure based discovery of anticancer agentsDesign and synthesis of heterocyclic compounds as antimalarial agents
Synthesis of heterocyclic compounds, Multicomponent reactions (MCR), Tin free radical reactions, Synthetic use of organoboron compounds, Green Chemistry
PublicationsDr. Sankar K. Guchhait
Assistant Professor
Department of Medicinal Chemistry
National Institute of Pharmaceutical Education and Research (NIPER)
Phase X, Sector 67, S. A. S. Nagar (Mohali), Punjab-160062, India.
17. An Efficient Regioselective Versatile Synthesis of N‐Fused 2‐ and 3‐Aminoimidazoles via Ugitype
Multicomponent Reaction Mediated by Zirconium(IV) Chloride in Polyethylene Glycol‐
400, Sankar K. Guchhait and Chetna Madaan Synlett 2009, 628.
1Click Chemistry: A Novel Approach in Drug Discovery, Chetna Madaan and Sankar K.
Guchhait CRIPS, 2008, 9, 11
15. Synthesis and structure‐activity relationships of metal‐ligand complexes that potently
inhibit cell migration, Anwar B. Beshir, Sankar K. Guchhait, José A. Gascón and Gabriel
Fenteany Bioorg. Med. Chem. Lett. 2008, 18, 498.
14. Green Chemistry: Its Potential Use in Sustainable Synthesis of Pharmaceuticals, Chetna
Madaan and Sankar K. Guchhait CRIPS, 2007, 8, 68
13. Convenient Synthesis of α,β‐Unsaturated Phosphonates via a Mizoroki‐Heck Reaction of
Arylboronic Acids with Diethyl vinylphosphonate, George W. Kabalka, Sankar K. Guchhait
and Abhijit Naravane Tetrahedron Lett . 2004, 45, 4685.
12. Convenient Synthesis of α,β‐Unsaturated Sulfones via a Mizoroki‐Heck Reaction of
Arylboronic Acids with Phenyl Vinyl Sulfones, George W. Kabalka and Sankar K. Guchhait,
Tetrahedron Lett . 2004, 45, 4021.
11. Synthesis of Diprotected Monosubstituted Hydrazine Derivatives from tert‐Butyl Carbazates
and Boronic Acids, George W. Kabalka and Sankar K. Guchhait, Org. Lett. 2003, 5, 4129.
10. Synthesis of (E)‐ and (Z)‐Alkenylphosphonates Using Vinylboronates, George W. Kabalka and
Sankar K. Guchhait, Org. Lett. 2003, 5, 729.
9. Zinc Tetrafluoroborate Catalyzed Mannich‐Type Reaction of Aldimines and Silyl Enol Ethers
in Aqueous Medium, Brindaban C. Ranu, Sampak Samanta and Sankar K. Guchhait,
Tetrahedron 2002, 58, 983.
8. Selective Reduction of Terminal Alkynes to Alkenes by Indium Metal, Brindaban C. Ranu,
Jyotirmoy Dutta and Sankar K. Guchhait, J. Org. Chem. 2001, 66, 5624.
7. Indium Metal as a Reducing Agent. Selective Reduction of Carbon‐Carbon Double Bond in
Highly Activated Conjugated Alkenes, Brindaban C. Ranu, Jyotirmoy Dutta and Sankar K.
Guchhait, Org. Lett. 2001, 3, 2603.
6. Stereoselective Reduction of Aryl‐Substituted gem‐Dibromides to Vinyl Bromides by Indium
Metal, Brindaban C. Ranu, Sampak Samanta and Sankar K. Guchhait, J. Org. Chem. 2001, 66,
4102.
5. Construction of Bicyclo[2.2.2]octanone Systems by Microwave‐Assisted Solid Phase Michael
Addition Followed by Al2O3‐Mediated Intramolecular Aldolisation. An Eco‐friendly
Approach, Brindaban C. Ranu, Sankar K. Guchhait, Keya Ghosh and Amarendra Patra, Green
Chemistry, 2000, 5.
4. A Convenient and Efficient Procedure for Selective Deprotection of Acetates by Titanium(IV)
Isopropoxides, Brindaban C. Ranu, Sankar K. Guchhait and Manika Saha, J. Indian Chem.
Soc. 1999, 76, 547 (special issue dedicated to Professor D. Nasipuri, India on the occasion of
his 75th birth anniversary)
3. Stereoselective Debromination of Aryl‐Substituted vic‐Dibromide with Indium Metal,
Brindaban C. Ranu, Sankar K. Guchhait and Arunkanti Sarkar, J. Chem. Soc., Chem.
Commun., 1998, 2113.
2. Chemoselective Hydrogenation of α, β‐Unsaturated Sulfones and Phosphonates via
Palladium‐Assisted Hydrogen Transfer by Ammonium Formate, Brindaban C. Ranu, Sankar
K. Guchhait and Keya Ghosh, J. Org. Chem. 1998, 63, 5250.
1. Catalytic Hydrogen Transfer Reductions Using Ammonium Formate. A Review, Brindaban C.
Ranu, Arunkanti Sarkar, Sankar K. Guchhait and Keya Ghosh, J. Indian Chem. Soc. 1998, 75,
690‐694 (special issue dedicated to Professor Sukh Dev, India on the occasion of his 75th
birthday).
Getting Started
Need Help?